Antiretroviral Treatment

Treatment 2015

Published by: 
UNAIDS

The Joint United Nations Programme on HIV/AIDS (UNAIDS) has launched a new framework to accelerate action in reaching 15 million people with antiretroviral treatment by 2015––the goal set by United Nations Member States in 2011. 

The framework, entitled Treatment 2015, offers countries and partners both practical and innovative ways to increase the number of people accessing antiretroviral medicines. These medicines will not only enable people living with HIV to live longer and healthier lives, they will also help prevent new HIV infections.

Linkage to Care following Home-based HIV Counselling and Testing

Published by: 
Medical Research Council

Timely linkage to care and treatment by HIV-positive individuals can lead to significant decreases in morbidity and mortality as well as increases in life expectancy and quality of life. Further, there are significant prevention benefits as early initiation on antiretroviral treatment (ART) can significantly reduce HIV transmission to uninfected partners. Modeling exercises also suggest that universal HIV testing coupled with immediate treatment could decrease HIV incidence and virtually eliminate the HIV/AIDS pandemic. To achieve this, the rate of linkage to care must be 100%. This underscores the importance of understanding and addressing barriers to linkage.

NIMART rollout to primary healthcare facilities increases access to antiretrovirals in Johannesburg: An interrupted time series analysis

Volume: 
103(4):232-236
Series Name: 
SAMJ
Published by: 
SAMJ

Introduction. South Africa has made remarkable progress in rolling out antiretroviral therapy (ART), with the largest number of people (more than 1.4 million) enrolled on antiretrovirals in the world. Decentralisation of services to primary health centres (PHCs) has strengthened retention of patients on ART and reduced the burden of managing uncomplicated cases at referral hospitals.

Together we will end AIDS

Published by: 
UNAIDS

This new UNAIDS report contains the latest data on numbers of new HIV infections, numbers of people receiving antiretroviral treatment, AIDS-related deaths and HIV among children. It highlights new scientific opportunities and social progress which are bringing the world closer to UNAIDS vision of zero new HIV infections, zero discrimination and zero AIDS-related deaths.

The report also gives an overview of international and domestic HIV investments and the need for greater value for money and sustainability.

Calling for global solidarity and shared responsibility, the UNAIDS report contains commentaries from global and community leaders as well as people living with and affected by HIV.

An Economic Evaluation of the Impact of Widespread Antiretroviral Treatment on Secondary Hospitals in South Africa: Case Study of the GF Jooste Hospital Antiretroviral Referral Unit

Published by: 
Health Systems Trust

This research presents a partial economic evaluation of the current and anticipated impact of widespread antiretroviral treatment on the secondary hospital system in South Africa. The evaluation encompasses the treatment and care of HIV-positive inpatients and outpatients on or preparing for highly active antiretroviral therapy (HAART) at the secondary level. This study was conducted based on analysis of the Antiretroviral Referral Unit at GF Jooste Hospital during March 2005, and utilises a combination of current and retrospective data sets.

Monitoring and Evaluation of the Operational Plan for Comprehensive HIV and AIDS Care, Management and Treatment for South Africa - TRAINING MANUAL FOR FACILITATORS

Published by: 
Health Systems Trust
The National Department of Health funded (Tender NDOH28/2004-2005) the training project on monitoring and evaluation aspects of the Comprehensive HIV and AIDS Plan. This training manual was developed for the National Department of Health. Compilation of this manual was based on the Department of Healths documents - Data Flow and Data Management Protocol, Monitoring and Evaluation Framework, Technical Notes: Indicators and Definitions, National Antiretroviral Treatment Guidelines and the Operational Plan for Comprehensive HIV and AIDS Care, Management and Treatment for South Africa - by a team consisting of members from Health Systems Trust (HST) and the Health Information Systems Programme (HISP).

Monitoring and Evaluation of the Operational Plan for Comprehensive HIV and AIDS Care, Management and Treatment for South Africa - TRAINING MANUAL FOR PARTICIPANTS

Published by: 
Health Systems Trust
The National Department of Health funded (Tender NDOH28/2004-2005) the training project on monitoring and evaluation aspects of the Comprehensive HIV and AIDS Plan. This training manual was developed for the National Department of Health. Compilation of this manual was based on the Department of Healths documents - Data Flow and Data Management Protocol, Monitoring and Evaluation Framework, Technical Notes: Indicators and Definitions, National Antiretroviral Treatment Guidelines and the Operational Plan for Comprehensive HIV and AIDS Care, Management and Treatment for South Africa - by a team consisting of members from Health Systems Trust (HST) and the Health Information Systems Programme (HISP).

Providing Antiretroviral Treatment in Southern Africa - A Literature Review

Published by: 
Health Systems Trust

This report outlines experience with ART in a number of sub-Saharan countries. ART is provided through a number of different avenues, which include the public sector, the non-profit sector, the corporate sector and the private sector. ART programmes may involve collaboration between two or more sectors with such partnerships being encouraged in recognition that the magnitude of the task may exceed the capacity of any one sector. Particular attention is paid to Botswana, the first sub-Saharan country to provide ART on a wide-scale through the public sector.

Cost-Effectiveness of Antiretroviral Treatment for HIV-Positive Adults in a South African Township

Published by: 
Health Systems Trust
Introduction: This study aims to establish the costs and effectiveness of antiretroviral therapy (ART) for HIV positive adults in a resource-constrained public-sector setting. The research compares ART to the current status quo for HIV-positive adults who are dependent on the public sector for care in South Africa i.e the treatment of opportunistic and HIV- elated infections and events (e.g. wasting) in the absence of ART. This research is clearly important in the developing country context, where the HIV epidemic is expected to have a dramatic impact on life expectancy and to lead to early mortality for a large proportion of the population (Dorrington, Bourne et al. 2001). This study presents the first cost-effectiveness results derived from a public sector clinic-based treatment programme. Cost, effectiveness and quality of life data have been collected from a single cohort receiving care in three HIV-dedicated clinics in Khayelitsha, a township on the outskirts of Cape Town. This setting is similar to what will be encountered in the public sector ART rollout.