Tuberculosis

Risk of TB doubles in first year of HIV infection

The risk of developing tuberculosis doubles within the first year of testing HIV positive, according to a large retrospective study published in the January 15th issue of The Journal of Infectious Diseases. This risk further increased in subsequent years.

Rates of TB treatment interruption unaffected by HIV infection or HAART

HIV-positive patients receiving treatment for tuberculosis (TB) do not interrupt TB treatment more frequently than HIV-negative patients, although highly active antiretroviral therapy (HAART) does increase the incidence of side-effects, according to a case note review of patients at a London hospital. These findings were presented this week at the Seventh International Congress on Drug Therapy in HIV Infection in Glasgow.

TB treatment: four month continuation phase better than six months

The publication of an international study shows that six months of continuation phase treatment with isoniazid and ethambutol results in higher rates of relapse after treatment when compared to a four month continuation phase using isoniazid and rifampicin. The International Union Against Tuberculosis and Lung Disease and the United Kingdom Medical Research Council designed the study.