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Cost-Effectiveness of Antiretroviral Treatment for HIV-Positive Adults in a South African Township

Research

 

Publication Information

1st Author : Cleary, S
Other Authors: Boulle A , McIntyre D, Coetzee D
Publisher: Health Systems Trust
Publication Date: 11/2003
ISBN:
ISSN:
Publication Type: Research Report
Series:
Issue:

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Cost-effectiveness of ARV 935 KB
Cost-effectiveness of ARV - Summary 62 KB
 

Summary Introduction: This study aims to establish the costs and effectiveness of antiretroviral therapy (ART) for HIV positive adults in a resource-constrained public-sector setting. The research compares ART to the current status quo for HIV-positive adults who are dependent on the public sector for care in South Africa i.e the treatment of opportunistic and HIV- elated infections and events (e.g. wasting) in the absence of ART. This research is clearly important in the developing country context, where the HIV epidemic is expected to have a dramatic impact on life expectancy and to lead to early mortality for a large proportion of the population (Dorrington, Bourne et al. 2001). This study presents the first cost-effectiveness results derived from a public sector clinic-based treatment programme. Cost, effectiveness and quality of life data have been collected from a single cohort receiving care in three HIV-dedicated clinics in Khayelitsha, a township on the outskirts of Cape Town. This setting is similar to what will be encountered in the public sector ART rollout.
More Details

Background to this report

This report is the product of research into the cost-effectiveness and cost-utility of treatment for HIV-positive adults. The research was conducted in three HIVdedicated clinics in Khayelitsha, a township on the outskirts of Cape Town. The formal objectives of the research were to:

  • Describe the costs of providing antiretroviral treatment (ART) at primary care clinics
  • Describe the costs of providing care for HIV in the absence of ART at primary care clinics
  • Determine the associated health care costs for patients with HIV referred to other levels of care
  • Describe the effectiveness of ART and no-ART (i.e. treatment in the absence of ART) in terms of life years (LYs) gained and quality adjusted life years gained (QALYs)
  • Describe the cost-effectiveness and cost-utility of ART and no-ART in this setting
  • Describe the incremental cost-effectiveness and cost-utility of ART
  • Describe the incremental cost-effectiveness of different starting times of ART

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